最新快訊：
Fluoroquinolone是泌尿道感染的一項利器，但是因為可能發生嚴重且永久性的副作用，所以要減少使用它了。FDA說，若有其他的抗生素可選，請不要用fluoroquinolone，這不是幾乎判fluoroquinolone出局了嗎？
Fluoroquinolone Antibacterial Drugs: Drug Safety Communication - FDA Advises Restricting Use for Certain Uncomplicated Infections
http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm500665.htm
[Posted 05/12/2016]
AUDIENCE: Internal Medicine, Family Practice, Pharmacy, Patient
ISSUE: FDA is advising that the serious side effects associated with fluoroquinolone antibacterial drugs generally outweigh the benefits for patients with sinusitis, bronchitis, and uncomplicated urinary tract infections who have other treatment options. For patients with these conditions, fluoroquinolones should be reserved for those who do not have alternative treatment options.
An FDA safety review has shown that fluoroquinolones when used systemically (i.e. tablets, capsules, and injectable) are associated with disabling and potentially permanent serious side effects that can occur together. These side effects can involve the tendons, muscles, joints, nerves, and central nervous system.
有使用fluoroquinolone的患者，若是有關節、肌腱、肌肉疼痛，或是針刺痛感或是刺麻感，或是神智不清、幻覺現象時，要注意是否為藥物的副作用。
RECOMMENDATION: Patients should contact your health care professional immediately if you experience any serious side effects while taking your fluoroquinolone medicine. Some signs and symptoms of serious side effects include tendon, joint and muscle pain, a “pins and needles” tingling or pricking sensation, confusion, and hallucinations.
The panel voted 21-0 to update the warnings for sinusitis treatment, 18-2 (1 abstention) for bronchitis, and 20-1 for urinary tract infections. T
Asked to comment, infectious disease expert Dr. Paul Sax said: "While fluoroquinolones are usually safe, there is an increasing appreciation that rarely they may cause severe and sometimes permanent side effects. The additional warnings will be a reminder that no antibiotic should be used unless clearly indicated."
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