常用的止痛藥(NSAID)又有壞消息了，除了常見胃腸、腎臟副作用和之前說過的MI住院外，可能會再導致病人因心臟衰竭(heart failure)而住院。
BMJ期刊在2000-2010年，收了820萬個病人使用NSAID，共有9.2萬人因心臟衰竭而住院，經過和對照組比較後發現以下結果：
Current (use in preceding 14 days) use of any NSAID was associated with a 19% higher risk for heart failure hospitalization. The following individual, FDA-approved NSAIDs carried higher heart failure risk: ketorolac (odds ratio, 1.83), indomethacin (1.51), piroxicam (1.27), diclofenac (1.19), ibuprofen (1.18), and naproxen (1.16). The results were significant in patients regardless of their history of heart failure. Higher doses were associated with greater risk.
Non-steroidal anti-inflammatory drugs and risk of heart failure in four European countries: nested case-control study
BMJ 2016; 354 doi: http://dx.doi.org/10.1136/bmj.i4857 (Published 28 September 2016)
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