Effects of Intermittent Fasting on Health, Aging, and Disease
N Engl J Med 2019; 381:2541-2551 DOI: 10.1056/NEJMra1905136
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September 28, 2020
Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity
The TREAT Randomized Clinical Trial
JAMA Intern Med. 2020;180(11):1491-1499. doi:10.1001/jamainternmed.2020.4153
Finally, the DXA analysis of lean mass did not factor in muscle hydration, so it is possible that changes
in hydration could confound the lean mass calculations. To help control for this, participants fasted for more than 12 hours and voided their bladder prior to DXA scans. The change in lean mass in the TRE group was much greater than the loss of body water, so it is unlikely that differences in muscle hydration would account for all of the lean mass loss.